Interferon beta-1b Extavia (Novartis) Betaferon (Bayer)
The first drug that was approved for treatment of MS, interferon beta-1b inflammation in the central nervous system.
The most common side effects include injection site reactions and GI symptoms, such as stomach pain, constipation, and diarrhoea
Interferon beta-1a Avonex (Biogen) Rebif (Serono) An injectable medication, interferon beta-1a reduces inflammation, possibly through the reduction of T cell production and also reduction of inflammatory cells in the CNS. Like interferon beta- 1b, it is believed to prevent the crossing of inflammatory cells through the blood-brain barrier
The most common side effects include injection site reactions and fevers
Glatiramer acetate (Copaxone by Teva) This immunomodulator is used to prevent relapses.
The most common side effects include injection site reactions, fevers, double vision, weakness, and swelling of the hands or feet
Dimethyl Fumarate (Tecfidera by Biogen) This works as an anti-inflammatory by blocking cytokine induction.
The most common side effects include flushing, rash, and GI symptoms
Peginterferon beta-1a (Plegridy by Biogen) Similar to interferon is believed to have an extended duration.
The most common side effects include injection site reactions, fevers. and joint pain
Daclizumab (Zinbryta by Biogen)
This medication is believed to reduce T cells. The suggested mechanism is through binding to the IL- 2 T cell receptors
The most common side effects include upper respiratory tract infection and skin rash
Teriflunomide (Aubagio by Sanofi Genzyme)
This immunomodulatory drug is believed to work by inhibiting the proliferation of T cells and B cells.
It may cause abnormal liver tests, flu-like symptoms, and thinning hair
When it comes down to awareness-raising and thought-provoking initiatives in the health charity sector, fresh ideas are often hard to find.
Not so for Joan, a dear friend of mine. After her original Selfie Book idea created by her regional MS branch for World MS Day in 2015, Joan wanted to expand this Facebook idea and create a book for newly diagnosed people. Her own diagnosis – raw, no counselling, no management plan or words of inspiration from others who already walked down the same path, was something she wished had gone differently. In short, Joan was looking for a sign of hope, and something “telling me how people can get on with living a good life and that it wasn’t the end.”
You know you’re on to something when you recognise your medical file from afar, even when it’s tucked between 15 other colourful medical records.
Sadly, this is a fact that even World MS Day on Wednesday, May 30th can’t heal. Nevertheless, as a global community of approximately 2.3 million people with MS, being part of the solution – a.k.a. spreading awareness and pushing for a cure – can be infinitely rewarding. On WMSD, I feel an even greater purpose to be part of that solution, whether it is by attending disability-related meetings and spreading the word afterwards, or simply by becoming more conscious of the problems people with MS and other disabilities are facing in the world today.
Have you ever wondered, “What exactly is my purpose on our little shining blue ball floating around in our vast universe?”
Congratulations, so have I!
It took me the better part of my teenage years – if not very young adult life – to get to the stage where I thought, “Yes! Eureka! Yes, I found out what I am doing here!”
Translated, it sounded more like this, “I know where I am going to live!”
Part of the master plan that had been hiding in my unconscious mind had already been set in motion, albeit drifting rebelliously between my conscious and the harder to access unconscious level, before mischievously appearing again.